CLEC5A

CLEC5A
Gene
HUGO	CLEC5A CLECSF5; MDL-1; MDL1
Entrez	23601
Locus	Chr. 7 q34
Proteina
OMIM	604987
UniProt	Q9NY25
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CLEC5A (abbreviazione dell'inglese C-type LECtin domain family 5 member A) è una lectina che sembra avere un ruolo significativo nella attivazione della linea mieloide dell'emopoiesi.

Note

↑ Entrez Gene: C-type lectin domain family 5, su ncbi.nlm.nih.gov.
↑ Bakker AB, Baker E, Sutherland GR, Phillips JH, Lanier LL, Myeloid DAP12-associating lectin (MDL)-1 is a cell surface receptor involved in the activation of myeloid cells, in Proc. Natl. Acad. Sci. U.S.A., vol. 96, agosto 1999, pp. 9792–6, DOI:10.1073/pnas.96.17.9792, PMC 22289, PMID 10449773.

Bibliografia

Chen ST, Lin YL, Huang MT, et al., CLEC5A is critical for dengue-virus-induced lethal disease., in Nature, vol. 453, 2008, pp. 672–6, DOI:10.1038/nature07013, PMID 18496526.
Davila S, Froeling FE, Tan A, et al., New genetic associations detected in a host response study to hepatitis B vaccine., in Genes Immun., vol. 11, 2010, pp. 232–8, DOI:10.1038/gene.2010.1, PMID 20237496.
Scherer SW, Cheung J, MacDonald JR, et al., Human chromosome 7: DNA sequence and biology., in Science, vol. 300, 2003, pp. 767–72, DOI:10.1126/science.1083423, PMC 2882961, PMID 12690205.
Hillier LW, Fulton RS, Fulton LA, et al., The DNA sequence of human chromosome 7., in Nature, vol. 424, 2003, pp. 157–64, DOI:10.1038/nature01782, PMID 12853948.
Ebner S, Sharon N, Ben-Tal N, Evolutionary analysis reveals collective properties and specificity in the C-type lectin and lectin-like domain superfamily., in Proteins, vol. 53, 2003, pp. 44–55, DOI:10.1002/prot.10440, PMID 12945048.
Gerhard DS, Wagner L, Feingold EA, et al., The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)., in Genome Res., vol. 14, 2004, pp. 2121–7, DOI:10.1101/gr.2596504, PMC 528928, PMID 15489334.
Strausberg RL, Feingold EA, Grouse LH, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences., in Proc. Natl. Acad. Sci. U.S.A., vol. 99, 2002, pp. 16899–903, DOI:10.1073/pnas.242603899, PMC 139241, PMID 12477932.
Drickamer K, C-type lectin-like domains., in Curr. Opin. Struct. Biol., vol. 9, 1999, pp. 585–90, DOI:10.1016/S0959-440X(99)00009-3, PMID 10508765.
Watson AA, O'Callaghan CA, Crystallization and X-ray diffraction analysis of human CLEC5A (MDL-1), a dengue virus receptor., in Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun., vol. 66, 2010, pp. 29–31, DOI:10.1107/S1744309109047915, PMID 20057064.

Portale Biologia

Portale Medicina

[entrez-1] Entrez Gene: C-type lectin domain family 5, su ncbi.nlm.nih.gov.

[pmid10449773-2] Bakker AB, Baker E, Sutherland GR, Phillips JH, Lanier LL, Myeloid DAP12-associating lectin (MDL)-1 is a cell surface receptor involved in the activation of myeloid cells, in Proc. Natl. Acad. Sci. U.S.A., vol. 96, agosto 1999, pp. 9792–6, DOI:10.1073/pnas.96.17.9792, PMC 22289, PMID 10449773.

CLEC5A
Gene
HUGO	CLEC5A CLECSF5; MDL-1; MDL1
Entrez	23601
Locus	Chr. 7 q34
Proteina
OMIM	604987
UniProt	Q9NY25
Modifica dati su Wikidata · Manuale