February 6– In the battle of Kerestinec, General Gašpar Alapić defeats the rebel troops led by Gubec.
February 9– Croatian troops, led by General Alapic, defeat the peasant rebellion in the Battle of Stubica, then begin a violent campaign of vengeance against the conquered rebels. Rebellion leaders Matija Gubec and Ivan Pasanec are taken as prisoners of war for a trial for treason at Zagreb.
February 23– In the province of Munster in Ireland, the first Desmond Rebellion, led by James FitzMaurice FitzGerald, cousin of the Earl of Desmond, ends at Kilmallock as FitzGerald makes a humiliating surrender to John Perrot, the provincial leader.
April 9– The Siege of Sommières ends with the surrender of the Huguenot defenders, who are spared retaliation by General Montmorency, despite the loss of 2,500 royal troops.
April 22–Eighty Years' War: The Battle of Borsele is fought as a fleet of Spanish ships is intercepted by Dutch Calvinist rebels (the Geuzen). While some of the ships are able to complete their mission of supplying the Spanish-governed Netherlands cities of Middelburg and Arnemuiden, most are forced to retreat to Amberes in the Spanish Netherlands, now Antwerp in Belgium.
June 24– After Henry, Duke of Anjou learns that he has been elected the King of Poland, he agrees to negotiate an end to the Siege of La Rochelle, which has continued for almost nine months against the Huguenots in the western French city, and reaches an agreement with the Huguenot defender, the Count of Montgomery.
November 29– The Duke of Alva resigns as the Spanish Governor-General of the Netherlands, and is succeeded by Luis de Requesens, who attempts to pursue a more conciliatory policy.
December 3– The French Duke of Anjou, recently elected as King Henry of Poland, departs from Metz with an entourage of 1,200 people, arriving at Kraków on February 18.
December 11– The Governor of Portuguese India issues an edict depriving Hindu followers of most rights, including the right to receive Jonoa, the share of the village community income.
December 17– Portuguese colonists are expelled from the Maldives, where Portugal has had a presence since 1558, by order of the Sultan's son, Mohamed Bodu Takurufanu al-Azam.
December 23– In the Republic of Venice, the Council of Ten votes to grant safe conduct to Venice for Spanish and Portuguese Jews.
The first Spanish galleon, laden with silver for the porcelain and silk trade with the Ming Dynasty of China, lands at Manila in the Philippines. This occasion marks the beginning of the Spanish silver trade to China, that will trump that of the Portuguese, the latter of whom acted as an intermediary between the silver mines of Japan, and the luxury items in China to be purchased with that silver. Most of the silver entering China comes from what is now Mexico, Bolivia, and Peru in the New World.