CEP104

CEP104
Identifiers
Aliases	CEP104, GlyBP, KIAA0562, CFAP256, JBTS25, ROC22, centrosomal protein 104
External IDs	OMIM: 616690; MGI: 2687282; GeneCards: CEP104
Gene location (Human)
Chr.	Chromosome 1 (human)
End	3,857,214 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	154,093,189 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; buccal mucosa cell; ; sperm; ; internal globus pallidus; ; saphenous vein; ; inferior ganglion of vagus nerve; ; islet of Langerhans; ; lactiferous duct; ; sural nerve; ; stromal cell of endometrium;
	Top expressed in
	olfactory epithelium; ; muscle of thigh; ; zygote; ; digastric muscle; ; triceps brachii muscle; ; temporal muscle; ; sternocleidomastoid muscle; ; skeletal muscle tissue; ; extraocular muscle; ; secondary oocyte;
	More reference expression data
	n/a
Orthologs
Databases	NCBI: entry; OMA: entry
	9731
	230967
	ENSG00000116198
	ENSMUSG00000039523
	O60308
	Q80V31
	NM_014704
	NM_177673
	NP_055519
	NP_808341
	Wikidata
View/Edit Human	View/Edit Mouse

Centrosomal protein 104kDa is a protein that in humans is encoded by the CEP104 gene. Like its Chlamydomonas ortholog, FAP256, it has been shown to localize to the distal ends of both centrioles in the absence of a cilium. During cilium formation, it is found at the tip of the elongating cilium.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000116198 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000039523 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Centrosomal protein 104kDa". Retrieved 2014-06-04.
↑ Satish Tammana TV, Tammana D, Diener DR, Rosenbaum J (November 2013). "Centrosomal protein CEP104 (Chlamydomonas FAP256) moves to the ciliary tip during ciliary assembly". Journal of Cell Science. 126 (Pt 21): 5018–29. doi:10.1242/jcs.133439. PMC 3820246. PMID 23970417.

External links

Human CEP104 genome location and CEP104 gene details page in the UCSC Genome Browser.
Overview of all the structural information available in the PDB for UniProt: O60308 (Centrosomal protein of 104 kDa) at the PDBe-KB.

Kumar KN, Babcock KK, Johnson PS, Chen X, Ahmad M, Michaelis EK (November 1995). "Cloning of the cDNA for a brain glycine-, glutamate- and thienylcyclohexylpiperidine-binding protein". Biochemical and Biophysical Research Communications. 216 (1): 390–8. doi:10.1006/bbrc.1995.2636. PMID 7488117.
Jakobsen L, Vanselow K, Skogs M, Toyoda Y, Lundberg E, Poser I, Falkenby LG, Bennetzen M, Westendorf J, Nigg EA, Uhlen M, Hyman AA, Andersen JS (April 2011). "Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods". The EMBO Journal. 30 (8): 1520–35. doi:10.1038/emboj.2011.63. PMC 3102290. PMID 21399614.

This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000116198 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000039523 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Centrosomal protein 104kDa". Retrieved 2014-06-04.

[6] Satish Tammana TV, Tammana D, Diener DR, Rosenbaum J (November 2013). "Centrosomal protein CEP104 (Chlamydomonas FAP256) moves to the ciliary tip during ciliary assembly". Journal of Cell Science. 126 (Pt 21): 5018–29. doi:10.1242/jcs.133439. PMC 3820246. PMID 23970417.

v t e The centrosome and its components
Centrioles	SASS6 CENPJ CNTROB CEP104 Centrins (CETN1, CETN2 and CETN3) SFI1
Pericentriolar material	BBS4 LCK PCM1 PCNT TNKS TNKS2 TUBE1
other proteins	CCP110 CEP55 CEP57 CEP63 CEP68 CEP70 CEP72 CEP76 CEP78 CEP90 CEP97 CEP120 CEP135 CEP152 CEP164 CEP170 CEP192 CEP215 CEP250 CEP350 CNTRL NIN NINL

CEP104

References

External links

Further reading