SFI1 Protein-coding gene in the species Homo sapiens
Sfi1 homolog, spindle assembly associated (yeast) is a protein that in humans is encoded by the SFI1 gene . It localizes to the centriole , and its S. pombe ortholog has been shown to be involved in spindle pole body duplication. SFI1 forms a complex with centrin 2 .
References
1 2 3 GRCh38: Ensembl release 89: ENSG00000198089 – Ensembl , May 20171 2 3 GRCm38: Ensembl release 89: ENSMUSG00000023764 – Ensembl , May 2017↑ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .↑ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .↑
"Entrez Gene: Sfi1 homolog, spindle assembly associated (yeast)" . Retrieved 2014-06-25 . ↑ Elserafy M, Šarić M, Neuner A, Lin TC, Zhang W, Seybold C, Sivashanmugam L, Schiebel E (July 2014). "Molecular mechanisms that restrict yeast centrosome duplication to one event per cell cycle" . Current Biology . 24 (13): 1456– 66. doi :10.1016/j.cub.2014.05.032 PMID 24954044 . ↑ Martinez-Sanz J, Kateb F, Assairi L, Blouquit Y, Bodenhausen G, Abergel D, Mouawad L, Craescu CT (January 2010). "Structure, dynamics and thermodynamics of the human centrin 2/hSfi1 complex" . Journal of Molecular Biology . 395 (1): 191– 204. doi :10.1016/j.jmb.2009.10.041 . PMID 19857500 .
Further reading
Martinez-Sanz J, Kateb F, Assairi L, Blouquit Y, Bodenhausen G, Abergel D, Mouawad L, Craescu CT (January 2010). "Structure, dynamics and thermodynamics of the human centrin 2/hSfi1 complex" . Journal of Molecular Biology . 395 (1): 191– 204. doi :10.1016/j.jmb.2009.10.041 . PMID 19857500 . Mayor T, Stierhof YD, Tanaka K, Fry AM, Nigg EA (November 2000). "The centrosomal protein C-Nap1 is required for cell cycle-regulated centrosome cohesion" . The Journal of Cell Biology . 151 (4): 837– 46. doi :10.1083/jcb.151.4.837 . PMC 2169446 PMID 11076968 . Petretti C, Savoian M, Montembault E, Glover DM, Prigent C, Giet R (April 2006). "The PITSLRE/CDK11p58 protein kinase promotes centrosome maturation and bipolar spindle formation" . EMBO Reports . 7 (4): 418– 24. doi :10.1038/sj.embor.7400639 . PMC 1456919 PMID 16462731 . Casenghi M, Meraldi P, Weinhart U, Duncan PI, Körner R, Nigg EA (July 2003). "Polo-like kinase 1 regulates Nlp, a centrosome protein involved in microtubule nucleation" . Developmental Cell . 5 (1): 113– 25. doi :10.1016/S1534-5807(03)00193-X PMID 12852856 . Ajuh P, Kuster B, Panov K, Zomerdijk JC, Mann M, Lamond AI (December 2000). "Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry" . The EMBO Journal . 19 (23): 6569– 81. doi :10.1093/emboj/19.23.6569 . PMC 305846 PMID 11101529 . Kilmartin JV (September 2003). "Sfi1p has conserved centrin-binding sites and an essential function in budding yeast spindle pole body duplication" . The Journal of Cell Biology . 162 (7): 1211– 21. doi :10.1083/jcb.200307064 . PMC 2173958 PMID 14504268 . Hendrickx A, Beullens M, Ceulemans H, Den Abt T, Van Eynde A, Nicolaescu E, Lesage B, Bollen M (April 2009). "Docking motif-guided mapping of the interactome of protein phosphatase-1" . Chemistry & Biology . 16 (4): 365– 71. doi :10.1016/j.chembiol.2009.02.012 PMID 19389623 . Takahashi M, Yamagiwa A, Nishimura T, Mukai H, Ono Y (September 2002). "Centrosomal proteins CG-NAP and kendrin provide microtubule nucleation sites by anchoring gamma-tubulin ring complex" . Molecular Biology of the Cell . 13 (9): 3235– 45. doi :10.1091/mbc.E02-02-0112 . PMC 124155 PMID 12221128 . Golsteyn RM, Mundt KE, Fry AM, Nigg EA (June 1995). "Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function" . The Journal of Cell Biology . 129 (6): 1617– 28. doi :10.1083/jcb.129.6.1617 . PMC 2291169 PMID 7790358 . Rüthnick D, Vitale J, Neuner A, Schiebel E (March 2021). "The N-terminus of Sfi1 and yeast centrin Cdc31 provide the assembly site for a new spindle pole body" . J Cell Biol . 220 (3). doi :10.1083/jcb.202004196 . PMC 7852455 PMID 33523111 .
External links
Overview of all the structural information available in the PDB for UniProt : A8K8P3 (Protein SFI1 homolog) at the PDBe-KB .
