On 27 September 2020, Hugo made his professional debut in a 1–1 draw between Flamengo and Palmeiras. He was selected as the Man of the Match.
On 12 January 2023, Hugo Souza transferred to Vissel Kobe for a transfer fee of €1.2 million, with Flamengo retaining 50% of any future transfer. However, two days later, Hugo withdrew from the transfer, citing personal problems.
Chaves (loan)
On 2 July 2023, Hugo Souza moved on a one-year loan to Primeira Liga club Chaves.
On 26 November 2024, Hugo transferred to Corinthians on a four-year contract, for a transfer fee of €800 thousand, after a four month loan.
International career
On 17 August 2018, Brazil national team manager Tite included Hugo in the 23-man roster for a pair of friendlies against the United States and El Salvador. However, he did not feature in either match.
On 26 May 2025, he returned to the Canarinho in Carlo Ancelotti's first call-up as coach of Brazil, ahead of the 2026 World Cup qualification matches against Ecuador and Paraguay. He was called up again for the last qualification matches against Chile and Bolivia, but didn't play either. He received his first cap in a 14 October friendly against Japan in Tokyo, which ended in a 3-2 defeat, Brazil's first ever against the Japanese. While the first two goals were attributed to mistakes committed by Fabrício Bruno, some blamed Souza for the third one, since he deflected a header by Ayase Ueda into his own net. Coincidentally, the last time a Corinthians goalkeeper played for Brazil was also in a friendly against Japan, when Cássio came in as a substitute in November 2017.
Souza was ultimately left out of Ancelotti's final squad for the World Cup, which included Alisson, Ederson and Weverton, the latter of which was considered more experienced.
Career statistics
Club
As of match played 5 November 2026
Appearances and goals by club, season and competition
↑Gondim, Fernanda (14 October 2025). "Web aponta falha grave de Hugo Souza em virada do Japão sobre Brasil"[Web points serious mistake by Hugo Souza in Japan's comeback over Brazil]. Web aponta falha grave de Hugo Souza em virada do Japão sobre Brasil (in Brazilian Portuguese). Retrieved 14 October 2025.