Vesicular inhibitory amino acid transporter

SLC32A1
Identifiers
Aliases	SLC32A1, VGAT, VIAAT, solute carrier family 32 member 1
External IDs	OMIM: 616440; MGI: 1194488; GeneCards: SLC32A1
Gene location (Human)
Chr.	Chromosome 20 (human)
End	38,729,372 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	158,457,668 bp
RNA expression pattern
	Top expressed in
	nucleus accumbens; ; putamen; ; prefrontal cortex; ; caudate nucleus; ; endothelial cell; ; external globus pallidus; ; cingulate gyrus; ; anterior cingulate cortex; ; middle temporal gyrus; ; right frontal lobe;
	Top expressed in
	dorsal tegmental nucleus; ; nucleus accumbens; ; nucleus of stria terminalis; ; lateral septal nucleus; ; superior colliculus; ; globus pallidus; ; central gray substance of midbrain; ; medulla oblongata; ; Rostral migratory stream; ; olfactory tubercle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	glycine transmembrane transporter activity; amino acid transmembrane transporter activity; gamma-aminobutyric acid:proton symporter activity;
Cellular component	integral component of membrane; membrane; synaptic vesicle; plasma membrane; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane; synapse; inhibitory synapse; synaptic vesicle membrane; presynaptic active zone; dendrite terminus; dendrite; cone cell pedicle; intracellular organelle; cell tip; neuron projection; neuron projection terminus; cytoplasmic vesicle membrane; cytoplasmic vesicle; integral component of synaptic vesicle membrane; GABA-ergic synapse;
Biological process	amino acid transmembrane transport; ageing; ion transport; gamma-aminobutyric acid transport; neurotransmitter transport; hippocampus development; neurotransmitter secretion; glycine transport; neurotransmitter loading into synaptic vesicle;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	140679
	22348
	ENSG00000101438
	ENSMUSG00000037771
	Q9H598
	O35633
	NM_080552
	NM_009508
	NP_542119
	NP_033534
	Wikidata
View/Edit Human	View/Edit Mouse

Vesicular inhibitory amino acid transporter is a protein that in humans is encoded by the SLC32A1 gene.

The protein encoded by this gene is an integral membrane protein involved in gamma-aminobutyric acid (GABA) and glycine uptake into synaptic vesicles. The encoded protein is a member of amino acid/polyamine transporter family II.