Notes et références
- 1 2 Les valeurs de la masse et du nombre de résidus indiquées ici sont celles du précurseur protéique issu de la traduction du gène, avant modifications post-traductionnelles, et peuvent différer significativement des valeurs correspondantes pour la protéine fonctionnelle.
- ↑ Lombard DB, Alt FW, Cheng HL et al. Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation, Mol Cell Biol, 2007;27:8807–8814
- 1 2 Liu L, Nam M, Fan W et al. Nutrient sensing by the mitochondrial transcription machinery dictates oxidative phosphorylation, J Clin Invest, 2014;124:768–784
- ↑ Tseng AH, Shieh SS, Wang DL, SIRT3 deacetylates FOXO3 to protect mitochondria against oxidative damage, Free Radic Biol Med, 2013;63:222–234
- ↑ Qiu X, Brown K, Hirschey MD, Verdin E, Chen D, Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation, Cell Metab, 2010;12:662–667
- ↑ Yu W, Dittenhafer-Reed KE, Denu JM, SIRT3 protein deacetylates isocitrate dehydrogenase 2 (IDH2) and regulates mitochondrial redox status, J Biol Chem, 2012;287:14078–14086
- ↑ Zhang X, Ji R, Liao X et al. MicroRNA-195 regulates metabolism in failing myocardium via alterations in sirtuin 3 expression and mitochondrial protein acetylation, Circulation, 2018;137:2052-2067
- ↑ Hirschey MD, Shimazu T, Jing E et al. SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome, Mol Cell, 2011;44:177–190
- ↑ Paulin R, Dromparis P, Sutendra G et al. Sirtuin 3 deficiency is associated with inhibited mitochondrial function and pulmonary arterial hypertension in rodents and humans, Cell Metab, 2014;20:827–839
