3152 CT

3152 CT
Names
Preferred IUPAC name
3-[(Dimethylcarbamoyl)oxy]-N,N,N-trimethyl-5-{3-[3-(trimethylazaniumyl)phenoxy]propoxy}anilinium diiodide
Identifiers
3D model (JSmol)
  • InChI=1S/C18H23N3O4.2HI/c1-21(2)18(22)25-17-11-14(20)10-16(12-17)24-8-4-7-23-15-6-3-5-13(19)9-15;;/h3,5-6,9-12H,4,7-8,19-20H2,1-2H3;2*1H
    Key: KDBKYZAHSYSXLC-UHFFFAOYSA-N
  • [NH3+]c(c1)cccc1OCCCOc(cc([NH3+])c2)cc2OC(=O)N(C)C.[I-].[I-]
Properties
C24H37I2N3O4
Molar mass 685.386 g·mol−1
Appearance Solid
Melting point 182–184 °C (360–363 °F; 455–457 K)
Hazards
Lethal dose or concentration (LD, LC):
16 μg/kg (intravenous, mice)
8 μg/kg (intravenous, rabbits)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

3152 CT is an extremely toxic bisquaternary carbamate with powerful anticholinesterase action. It has an LD50 in rats and rabbits 10 times lower than that of the GB agent and, on a molar basis, is 30 times more toxic than the latter.

See also

References

  1. 1 2 3 4 "Method for methylating and quaternizing".
  2. ↑ LEVIN, AP; JANDORF, BJ (February 1955). "Inactivation of cholinesterase by compounds related to neostigmine". The Journal of Pharmacology and Experimental Therapeutics. 113 (2): 206–11. doi:10.1016/S0022-3565(25)11504-8. PMID 13234044.
  3. ↑ WILLIAM H. SUMMERSON - Deputy Commander for Scientific Activities, USA CmIC Research and Development Command, Washington, D. C.. The Chemical Warfare Threat. NONMILITARY DEFENSE - Chemical and Biological Defenses in Perspective. ACS, 1960.