Brazergoline

Brazergoline
Clinical data
Other namesLuvion; 2-Bromo-6-methylergoline-8β-methanol hexahydro-1H-azepine-1-carboxylate
Drug classSympatholytic; Antihypertensive; Vasodilator
ATC code
  • None
Identifiers
  • [(6aR,9R,10aR)-5-bromo-7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinolin-9-yl]methyl azepane-1-carboxylate
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC23H30BrN3O2
Molar mass460.416 g·mol−1
3D model (JSmol)
  • CN1C[C@@H](C[C@H]2[C@H]1CC3=C(NC4=CC=CC2=C34)Br)COC(=O)N5CCCCCC5
  • InChI=1S/C23H30BrN3O2/c1-26-13-15(14-29-23(28)27-9-4-2-3-5-10-27)11-17-16-7-6-8-19-21(16)18(12-20(17)26)22(24)25-19/h6-8,15,17,20,25H,2-5,9-14H2,1H3/t15-,17-,20-/m1/s1
  • Key:MMPCMJGFURZYOY-WRWLIDTKSA-N

Brazergoline (INNTooltip International Nonproprietary Name; synonym Luvion) is a drug described as a sympatholytic, antihypertensive, and vasodilator of the ergoline family which was never marketed. It was reportedly investigated as a component of a condom with penile erection-promoting effects and as a potential treatment for female sexual dysfunction. The drug was first described in the literature by 1976.

See also

References

  1. 1 2 Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. ISBN 978-1-4757-2085-3. Retrieved 6 May 2026.
  2. ↑ Negwer M (1994). Organic-chemical Drugs and Their Synonyms: (an International Survey). Akademie Verlag. p. 2213. ISBN 978-3-05-501629-5. Retrieved 6 May 2026.
  3. ↑ "Brazergoline Drug Profile". Ozmosi. 1 January 1900. Retrieved 6 May 2026.
  4. 1 2 "BRAZERGOLINE". Inxight Drugs. Retrieved 6 May 2026.