1Bz-LSD

1Bz-LSD
Clinical data
Other names1-Benzoyl-LSD; SYN-L-018
Routes of
administration		Oral
Drug classSerotonergic psychedelic; Hallucinogen
ATC code
  • None
Chemical and physical data
FormulaC27H28N3O2
Molar mass426.540 g·mol−1
3D model (JSmol)
  • CCN(CC)C(=O)[C]1CN(C)[C@@H]2Cc3cn(C(=O)c4ccccc4)c5cccc(C2=C1)c35
  • InChI=1S/C27H28N3O2/c1-4-29(5-2)26(31)20-14-22-21-12-9-13-23-25(21)19(15-24(22)28(3)16-20)17-30(23)27(32)18-10-7-6-8-11-18/h6-14,17,24H,4-5,15-16H2,1-3H3/t24-/m1/s1
  • Key:GVGINGNTVRBWSQ-XMMPIXPASA-N

1Bz-LSD, also known as 1-benzoyl-LSD or as SYN-L-018, is a psychedelic drug of the lysergamide family related to lysergic acid diethylamide (LSD). It is thought to be a prodrug of LSD. The drug was patented by Lizard Labs in 2024. Subsequently, it was encountered online as a novel designer drug in July 2024. 1Bz-LSD has been sold in the form of blotter tabs and microdots, for instance containing 10 μg and 200 μg doses per unit. A deethylated metabolite, 1Bz-LAE, has been identified. 1Bz-LSD was first described in the scientific literature by 2026. It is not an explicitly controlled substance in the United States or in Canada.

See also

References

  1. 1 2 3 4 5 "1Bz-LSD". AIPSIN (in Russian). Retrieved 1 January 2026.
  2. 1 2 3 4 Tanaka R, Kawamura M, Ito M, Kikura-Hanajiri R (April 2026). "Identification and Analysis of Lysergic Acid Diethylamide Analogs, 4-Benzoyl-N,N-Diethyl-7-Methyl-4,6,6a,7,8,9-Hexahydroindolo[4,3-fg]quinoline-9-Carboxamide (1Bz-LSD) and N,N-Diethyl-7-Methyl-4-(4-(Trimethylsilyl)Benzoyl)-4,6,6a,7,8,9-Hexahydroindolo[4,3-fg]quinoline-9-Carboxamide (1-TMSBz-LSD), in tablet or paper sheet products available online in Japan". Drug Test Anal. 18 (4): 510–517. doi:10.1002/dta.70039. PMID 41709646.
  3. 1 2 3 Azuma Y, Asada A, Tanaka M, Doi T (April 2026). "In Vitro Metabolism of 1-Benzoyl-Lysergic Acid Diethylamide (1Bz-LSD) and Identification of a Deethylated Metabolite (1Bz-LAE) Using a Synthesized Reference Standard". Drug Test Anal. 18 (4): 490–500. doi:10.1002/dta.70042. PMID 41700314.
  4. 1 2 3 WO 2024/028495, Stratford A, Williamson JP, "Prodrugs of Substituted Ergolines", published 8 February 2024, assigned to Synex Holdings BV
  5. ↑ Orange Book: List of Controlled Substances and Regulated Chemicals (January 2026) (PDF), United States: U.S. Department of Justice: Drug Enforcement Administration (DEA): Diversion Control Division, January 2026
  6. ↑ "Controlled Drugs and Substances Act". Department of Justice Canada. 5 December 2025. Retrieved 20 January 2026.