NBoc-DMT

NBoc-DMT
Clinical data
Other namesNB-DMT; DMT-BOC; N′-t-BOC-DMT; N′-tert-BOC-DMT; tert-BOC-DMT; N′-tert-Butoxycarbonyl-N,N-dimethyltryptamine
Drug classSerotonergic psychedelic; Hallucinogen; Serotonin receptor agonist; Serotonin 5-HT2A receptor agonist
Legal status
Legal status
  • Illegal in Russia
Identifiers
  • tert-butyl 3-[2-(dimethylamino)ethyl]-1H-indole-1-carboxylate
CAS Number
PubChem CID
Chemical and physical data
FormulaC17H24N2O2
Molar mass288.391 g·mol−1
3D model (JSmol)
  • CC(C)(C)OC(=O)N1C=C(C2=CC=CC=C21)CCN(C)C
  • InChI=1S/C17H24N2O2/c1-17(2,3)21-16(20)19-12-13(10-11-18(4)5)14-8-6-7-9-15(14)19/h6-9,12H,10-11H2,1-5H3
  • Key:IKVMWFRRDDILJA-UHFFFAOYSA-N

NBoc-DMT, or NB-DMT, also known as N1-tert-butoxycarbonyl-N,N-dimethyltryptamine, is a serotonergic psychedelic of the tryptamine family. It is a novel designer and recreational drug and is a synthetic modification of dimethyltryptamine (DMT) with an N′-tert-butyloxycarbonyl (NBoc) group.

NB-DMT is said to be a "prodrug" of DMT that decomposes into DMT when the compound is heated (e.g., with smoking or vaping). It may also be useful as an orally active prodrug of DMT, unlike DMT itself which is inactive when taken orally. NB-DMT has been claimed to have about 25% of the potency of DMT by weight. It was first detected as a designer drug being sold online by February 2024.

NB-DMT is a Schedule I controlled substance in Russia. The drug is not an explicitly controlled substance in the United States or in Canada. A number of other NBoc designer drugs have also been encountered.

See also

References

  1. 1 2 3 4 5 6 7 "DMT BOC (NB-DMT)". АИПСИН (AIPSIN) (in Russian). Retrieved 23 January 2025.
  2. 1 2 "Tert-butyl 3-[2-(dimethylamino)ethyl]indole-1-carboxylate". PubChem. U.S. National Library of Medicine. Retrieved 23 January 2025.
  3. ↑ US 2024/0116870, Alexander M, Duncton J, Clark S, "N,N-dimethyltryptamine and related psychedelics and uses thereof.", published 11 April 2024, assigned to Terran Biosciences Inc.
  4. ↑ WO 2024/121253, Buchner M, "Novel N,N-Dimethyltryptamine (DMT) derivatives and uses thereof.", published 13 June 2024, assigned to Mihkal GmbH
  5. ↑ Orange Book: List of Controlled Substances and Regulated Chemicals (January 2026) (PDF), United States: U.S. Department of Justice: Drug Enforcement Administration (DEA): Diversion Control Division, January 2026
  6. ↑ "Controlled Drugs and Substances Act". Department of Justice Canada. 5 December 2025. Retrieved 20 January 2026.
  7. ↑ Johnson CS, Bogun B (2019). "Chemical camouflage: illicit drug concealment using di-tert-butyldicarbonate". Australian Journal of Forensic Sciences. 51: S217–S219. doi:10.1080/00450618.2019.1569135. S2CID 86747489.