5-HO-MET

5-HO-MET
Clinical data
Other names5-OH-MET; 5-Hydroxy-MET; 5-Hydroxy-N-methyl-N-ethyltryptamine
Drug classSerotonergic psychedelic; Hallucinogen
ATC code
  • None
Identifiers
  • 3-[2-[ethyl(methyl)amino]ethyl]-1H-indol-5-ol
CAS Number
PubChem CID
Chemical and physical data
FormulaC13H18N2O
Molar mass218.300 g·mol−1
3D model (JSmol)
  • CCN(C)CCC1=CNC2=C1C=C(C=C2)O
  • InChI=1S/C13H18N2O/c1-3-15(2)7-6-10-9-14-13-5-4-11(16)8-12(10)13/h4-5,8-9,14,16H,3,6-7H2,1-2H3
  • Key:BQUBMTNAIITQAI-UHFFFAOYSA-N

5-HO-MET, also known as 5-hydroxy-N-methyl-N-ethyltryptamine, is a psychedelic drug of the tryptamine and 5-hydroxytryptamine families related to bufotenin (5-HO-DMT). It is the derivative of bufotenin in which one of the two methyl groups at the amine has been extended to an ethyl group. The drug is also an analogue of methylethyltryptamine (MET), 4-HO-MET (metocin), and 5-MeO-MET. 5-HO-MET was reported as a novel designer drug in Canada in 2025. Its predicted log P is 1.6, relative to 1.2 in the case of bufotenin.

See also

References

  1. 1 2 3 4 Rymill S, Candler L, Ramachandran P, Bacev-Giles C, Ngendabanka RJ, Racine S, et al. (2025). "New psychoactive substances (NPS) identified in Canada: Results of the online NPS survey (2020–2023)". Emerging Trends in Drugs, Addictions, and Health. 5 100178. doi:10.1016/j.etdah.2025.100178.
  2. ↑ "3-[2-[ethyl(methyl)amino]ethyl]-1H-indol-5-ol". PubChem. Retrieved 5 January 2026.
  3. ↑ "Bufotenine". PubChem. Retrieved 5 January 2026.