Panipenem/betamipron

Panipenem/betamipron
Combination of
PanipenemCarbapenem antibiotic
BetamipronInhibitor of renal panipenem uptake
Clinical data
Trade namesCarbenin
AHFS/Drugs.comInternational Drug Names
Routes of
administration		Intravenous
ATC code
Identifiers
CAS Number
PubChem CID
KEGG

Panipenem/betamipron is a carbapenem antibiotic marketed by Daiichi Sankyo Co. of Japan. It was launched in 1993, under the brand name Carbenin.

It is a combination in which panipenem is the carbapenem antibiotic and betamipron inhibits renal uptake of panipenem and so reduces its nephrotoxicity (much like the imipenem/cilastatin combination).

References

  1. ↑ Hikida M, Terashima S, Sato Y, Okamoato R, Inoue M (November 2001). "[Comparative antibacterial activity of carbapenems against P. aeruginosa (1)]". The Japanese Journal of Antibiotics. 54 (11): 571–9. doi:10.11553/antibiotics1968b.54.571. PMID 11828603.
  2. ↑ "Sankyo Launch". The Pharmaletter. 1994-01-24.
  3. ↑ International Drug Names: Carbenin.
  4. ↑ Finch RG (2003). Antibiotic and chemotherapy: anti-infective agents and their use in therapy. Elsevier Health Sciences. pp. 269ff. ISBN 978-0-443-07129-4. Retrieved 8 August 2011.
  5. ↑ Goa KL, Noble S (2003). "Panipenem/betamipron". Drugs. 63 (9): 913–25, discussion 926. doi:10.2165/00003495-200363090-00005. PMID 12678575. S2CID 263994230.