| abnormal dauer formation protein 7 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Organism | |||||||
| Symbol | daf-7 | ||||||
| Entrez | 175237 | ||||||
| Orthologs | NCBI: entry; OMA: entry | ||||||
| RefSeq (mRNA) | NM_064864.5 | ||||||
| RefSeq (Prot) | NP_497265.1 | ||||||
| UniProt | P92172 | ||||||
| Other data | |||||||
| Chromosome | III: 0.81 - 0.81 Mb | ||||||
| |||||||
The DAF-7 gene encodes for the ortholog of GDF11, a ligand of TGF-beta signaling pathway, in the worm Caenorhabditis elegans. When binds to the complex of type II receptor Daf-4 and type I receptor Daf-1, this receptor protein serine/threonine kinase will phosphorylation activate the Smad Protein Daf-8/14.