HLA-B55

major histocompatibility complex (human), class I, B55
Alleles B*5501, B*5502
Structure (See HLA-B)
Symbol(s) HLA-B
EBI-HLA B*5501
B*5502
Locus chr.6 6p21.31

HLA-B55 (B55) is an HLA-B serotype. B55 is a split antigen from the B22 broad antigen, sister serotypes are B54 and B56. The serotype identifies the more common HLA-B*55 gene products. (For terminology help see: HLA-serotype tutorial)

Serotype

B*55:03 is one of the four B alleles that reacts with neither Bw4 nor Bw6. The others are B*18:06, B*46:01, and B*73:01.

B55 and B22 serotype recognition of some HLA B*55 allele-group gene products
B*55B55 B22Sample
allele%%size (N)
5501925453
5502842309

Allele distribution

HLA B*5501 frequencies
freq
ref.Population(%)
India New Delhi3.8
Singapore Chinese Han3.5
Spain Eastern Andalusia Gipsy3.5
Georgia Tbilisi Kurds3.4
India North Delhi3.3
France South East3.1
Israel Arab Druse3.0
India North Hindus2.9
Georgia Tbilisi Georgians2.8
Russia Tuva (2)2.8
Georgia Svaneti Svans2.5
Iran Baloch2.5
Singapore Thai2.5
Sudanese2.5
Mexico Mestizos2.4
Spain Eastern Andalusia2.4
Ireland South2.0
Azores Central Islands1.8
Bulgaria1.8
Israel Ashkenazi and Non Ashkenazi Jews1.8
Oman1.7
Tunisia Tunis1.7
India Andhra Pradesh Golla1.4
China Tibet1.3
Uganda Kampala1.2
Finland1.1
Portugal North1.1
Portugal Centre1.0
Singapore Riau Malay1.0
B*5502
Taiwan Taroko14.5
American Samoa12.0
China Guangxi Maonan6.0
Japan Ainu Hokkaido5.0
China Tibet Autonomous Region Tibetans4.7
Singapore Chinese3.0
China Beijing Shijiazhuang Tianjian Han2.9
China North Han2.9
South Korea (3)2.7
Hong Kong Chinese2.2
Japan (5)2.2
Taiwan Ami2.0
Thailand (3)2.0
New Caledonia1.0
Philippines Ivatan1.0

References

  1. ↑ Marsh, S. G.; Albert, E. D.; Bodmer, W. F.; Bontrop, R. E.; Dupont, B.; Erlich, H. A.; Fernández-Viña, M.; Geraghty, D. E.; Holdsworth, R.; Hurley, C. K.; Lau, M.; Lee, K. W.; Mach, B.; Maiers, M.; Mayr, W. R.; Müller, C. R.; Parham, P.; Petersdorf, E. W.; Sasazuki, T.; Strominger, J. L.; Svejgaard, A.; Terasaki, P. I.; Tiercy, J. M.; Trowsdale, J. (2010). "Nomenclature for factors of the HLA system, 2010". Tissue Antigens. 75 (4): 291–455. doi:10.1111/j.1399-0039.2010.01466.x. PMC 2848993. PMID 20356336.
  2. ↑ Voorter, CE; van der Vlies, S; Kik, M; van den Berg-Loonen, EM (October 2000). "Unexpected Bw4 and Bw6 reactivity patterns in new alleles". Tissue Antigens. 56 (4): 363–70. doi:10.1034/j.1399-0039.2000.560409.x. PMID 11098937.
  3. ↑ derived from IMGT/HLA
  4. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database". Tissue Antigens. 61 (5): 403–7. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660.