HLA-B59




major histocompatibility complex (human), class I, B59
Alleles	B*5901
Structure (See HLA-B)
Symbol(s)	HLA-B
EBI-HLA	B*5901
Locus	chr.6 6p21.31

HLA-B59 (B59) is an HLA-B serotype. The serotype identifies the more common HLA-B*## gene products. B59 is a hybrid between B*55 and B*51. B59 is more common in Japan, Korea, N. China and Mongolia. (For terminology help see: HLA-serotype tutorial)

Serotype

B59 serotype recognition of the HLA B*59 allele-group gene products
B*59	B59	Other	Sample
allele	%	%	size (N)
5901	45	41	123

B*5901 allele frequencies

**HLA B*5901 frequencies**
		freq
ref.	Population	(%)
	Okinawan (USA Hawaii)	6.3
	Japan (2)	2.7
	Tarialan Khoton (Mongolia)	2.4
	South Korea (3)	2.1
	Gipuscoa Basque (Spain)	2.0
	Japan Central	1.8
	Casablanca (Morocco)	1.8
	Hyogo (Japan)	1.6
	N. Korean (Harbin, China)	1.0
	Manchu (Harbin, China)	0.6
	Naxi (Yunnan, China)	0.6
	Girona (Catalonia, Spain)	0.6
	Algeria (1)	0.5
	Inner Mongolia (China)	0.5
	Khalkha (Mongolia)	0.5
	Shanghai (China)	0.3
	Essen (German )	0.3
	Southern Han (China)	0.2
	Shij. Tian. (Beijing, China)	0.1
	Hakka (Taiwan)	0.1

**Regions of higher B*5901 frequency**
Japan
Korea
Mongolia
Heilongjiang prov., China (Harbin city)

References

↑ Marsh, S. G.; Albert, E. D.; Bodmer, W. F.; Bontrop, R. E.; Dupont, B.; Erlich, H. A.; Fernández-Viña, M.; Geraghty, D. E.; Holdsworth, R.; Hurley, C. K.; Lau, M.; Lee, K. W.; Mach, B.; Maiers, M.; Mayr, W. R.; Müller, C. R.; Parham, P.; Petersdorf, E. W.; Sasazuki, T.; Strominger, J. L.; Svejgaard, A.; Terasaki, P. I.; Tiercy, J. M.; Trowsdale, J. (2010). "Nomenclature for factors of the HLA system, 2010". Tissue Antigens. 75 (4): 291–455. doi:10.1111/j.1399-0039.2010.01466.x. PMC 2848993. PMID 20356336.
↑ Hildebrand WH, Domena JD, Parham P (1993). "Primary structure shows HLA-B59 to be a hybrid of HLA-B55 and HLA-B51, and not a subtype of HLA-B8". Tissue Antigens. 41 (4): 190–5. doi:10.1111/j.1399-0039.1993.tb02001.x. PMID 8362411.
↑ derived from IMGT/HLA
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database". Tissue Antigens. 61 (5): 403–7. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660.

[pmid15787720-1] Marsh, S. G.; Albert, E. D.; Bodmer, W. F.; Bontrop, R. E.; Dupont, B.; Erlich, H. A.; Fernández-Viña, M.; Geraghty, D. E.; Holdsworth, R.; Hurley, C. K.; Lau, M.; Lee, K. W.; Mach, B.; Maiers, M.; Mayr, W. R.; Müller, C. R.; Parham, P.; Petersdorf, E. W.; Sasazuki, T.; Strominger, J. L.; Svejgaard, A.; Terasaki, P. I.; Tiercy, J. M.; Trowsdale, J. (2010). "Nomenclature for factors of the HLA system, 2010". Tissue Antigens. 75 (4): 291–455. doi:10.1111/j.1399-0039.2010.01466.x. PMC 2848993. PMID 20356336.

[pmid8362411-2] Hildebrand WH, Domena JD, Parham P (1993). "Primary structure shows HLA-B59 to be a hybrid of HLA-B55 and HLA-B51, and not a subtype of HLA-B8". Tissue Antigens. 41 (4): 190–5. doi:10.1111/j.1399-0039.1993.tb02001.x. PMID 8362411.

[3] rived from IMGT/HLA

[pmid12753660-4] 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database". Tissue Antigens. 61 (5): 403–7. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660.