KIF9

KIF9
Identifiers
Aliases	KIF9, kinesin family member 9
External IDs	OMIM: 607910; MGI: 1098237; GeneCards: KIF9
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3NWN
Gene location (Human)
Chr.	Chromosome 3 (human)
End	47,283,451 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	110,354,247 bp
RNA expression pattern
	Top expressed in
	bronchial epithelial cell; ; sperm; ; caput epididymis; ; left testis; ; mucosa of paranasal sinus; ; right testis; ; right uterine tube; ; olfactory zone of nasal mucosa; ; tendon of biceps brachii; ; corpus epididymis;
	Top expressed in
	spermatid; ; spermatocyte; ; seminiferous tubule; ; olfactory epithelium; ; choroid plexus of lateral ventricle; ; choroid plexus of fourth ventricle; ; Epithelium of choroid plexus; ; vestibular sensory epithelium; ; oocyte; ; primary oocyte;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein dimerization activity; nucleotide binding; microtubule motor activity; protein binding; microtubule binding; ATP binding; ATPase activity;
Cellular component	cytoskeleton; vesicle; podosome; cytoplasm; kinesin complex; microtubule;
Biological process	extracellular matrix disassembly; regulation of podosome assembly; organelle disassembly; microtubule-based movement;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	64147
	16578
	ENSG00000088727
	ENSMUSG00000032489
	Q9HAQ2; Q6PJI1
	Q9WV04
NM_001134878; NM_022342; NM_182902; NM_182903; NM_001377474;
	NM_001377475; NM_001377476; NM_001377477
	NM_001163569; NM_010628
NP_001128350; NP_071737; NP_878905; NP_001364403; NP_001364404;
	NP_001364405; NP_001364406
	NP_001157041; NP_034758
	Wikidata
View/Edit Human	View/Edit Mouse

Kinesin family member 9 (KIF9), also known as kinesin-9, is a human protein encoded by the KIF9 gene. It is part of the kinesin family of motor proteins.

Function

The beating of the flagella in sperm is regulated by KIF9 activity.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000088727 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000032489 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Miyata H, Shimada K, Morohoshi A, Oura S, Matsumura T, Xu Z, et al. (April 2020). "Testis-enriched kinesin KIF9 is important for progressive motility in mouse spermatozoa". FASEB Journal. 34 (4): 5389–5400. doi:10.1096/fj.201902755R. PMC 7136151. PMID 32072696.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000088727 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000032489 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[:0-5] Miyata H, Shimada K, Morohoshi A, Oura S, Matsumura T, Xu Z, et al. (April 2020). "Testis-enriched kinesin KIF9 is important for progressive motility in mouse spermatozoa". FASEB Journal. 34 (4): 5389–5400. doi:10.1096/fj.201902755R. PMC 7136151. PMID 32072696.