Squilla is active in Philadelphia Democratic politics, having held a variety of positions. In the 2004 Democratic primary, he unsuccessfully challenged incumbent State Representative William Keller for a seat in the State House. In 2011, he ran for City Council, seeking to succeed retiring Democrat Frank DiCicco in the First District. He ultimately came out on-top of a four-man Democratic primary field, and faced no opposition in the general election.
Squilla's wife, Brigid, is a nurse anesthetist. The couple has four children.
- Councilman Mark Squilla official city website