ACP2

ACP2
Tanımlayıcılar
Başka adlar	ACP2
Dış kimlikler	OMIM: 171650 MGI: 87882 HomoloGene: 1217 GeneCards: ACP2
Enzim Komisyon numarası	3.1.3.2
Gen yerleşimi (İnsan)
Krom.	11. Kromozom (insan)
Bitiş	47,248,906 bç
RNA ekspresyonu deseni
	Daha çok ekspresyon verisi başvurusu
Gen ontolojisi
Moleküler işlevi	• hydrolase activity; • acid phosphatase activity;
Hücresel bileşeni	• integral component of membrane; • lysosomal membrane; • Lizozom; • lysosomal lumen; • extracellular exosome; • membrane;
Biyolojik süreci	• skeletal system development; • lysosome organization; • GO:0098501, GO:0098502, GO:0006286 defosforilasyon;
	Kaynaklar:Amigo / QuickGO
Ortologlar
	53
	11432
	ENSG00000134575
	ENSMUSG00000002103
	P11117
	P24638
NM_001131064; NM_001302489; NM_001302490; NM_001302491; NM_001302492;
	NM_001610; NM_001357016
	NM_007387; NM_001357067
NP_001289418; NP_001289419; NP_001289420; NP_001289421; NP_001601;
	NP_001343945
	NP_031413; NP_001343996
	Vikiveri
İnsan'ı Gör/Düzenle	Fare'yi Gör/Düzenle

Lizozomal asit fosfataz, insanların 11. kromozomunda yer alan ACP2 geni tarafından kodlanan bir enzimdir.

Kaynakça

1 2 3 GRCh38: Ensembl release 89: ENSG00000134575 - Ensembl, May 2017
↑ "İnsan PubMed Başvurusu:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Fare PubMed Başvurusu:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Shows TB, Brown JA, Lalley PA (Dec 1976). "Assignment and linear order of human acid phosphatase-2, esterase A4, and lactate dehydrogenase A genes on chromosome 11". Cytogenet Cell Genet. 16 (1–5). ss. 231-4. doi:10.1159/000130598. PMID 975882.
↑ "Entrez Gene: ACP2 acid phosphatase 2, lysosomal". 2 Kasım 2008 tarihinde kaynağından arşivlendi.

Ek okuma

Moss DW, Raymond FD, Wile DB (1995). "Clinical and biological aspects of acid phosphatase". Critical Reviews in Clinical Laboratory Sciences. 32 (4). ss. 431-67. doi:10.3109/10408369509084690. PMID 7576159.
Gierek T, Lisiewicz T, Pilch J (1977). "Intracellular enzymatic response of lymphocytes and neutrophils in patients with cancer of the larynx". Folia Haematol. Int. Mag. Klin. Morphol. Blutforsch. 104 (2). ss. 208-15. PMID 69583.
Jones C, Kao FT (1979). "Regional mapping of the gene for human lysosomal acid phosphatase (ACP2) using a hybrid clone panel containing segments of human chromosome 11". Hum. Genet. 45 (1). ss. 1-10. doi:10.1007/BF00277567. PMID 730175.
Geier C, von Figura K, Pohlmann R (1989). "Structure of the human lysosomal acid phosphatase gene". Eur. J. Biochem. 183 (3). ss. 611-6. doi:10.1111/j.1432-1033.1989.tb21090.x. PMID 2776754.
Lemansky P, Gieselmann V, Hasilik A, von Figura K (1985). "Synthesis and transport of lysosomal acid phosphatase in normal and I-cell fibroblasts". J. Biol. Chem. 260 (15). ss. 9023-30. doi:10.1016/S0021-9258(17)39452-8. PMID 3160696.
Pohlmann R, Krentler C, Schmidt B, ve diğerleri. (1989). "Human lysosomal acid phosphatase: cloning, expression and chromosomal assignment". EMBO J. 7 (8). ss. 2343-50. doi:10.1002/j.1460-2075.1988.tb03078.x. PMC 457099 . PMID 3191910.
Waheed A, Van Etten RL (1985). "Biosynthesis and processing of lysosomal acid phosphatase in cultured human cells". Arch. Biochem. Biophys. 243 (1). ss. 274-83. doi:10.1016/0003-9861(85)90796-9. PMID 3904632.
Nadler HL, Egan TJ (1970). "Deficiency of lysosomal acid phosphatase. A new familial metabolic disorder". N. Engl. J. Med. 282 (6). ss. 302-7. doi:10.1056/NEJM197002052820604. PMID 5410815.
Bass DA, Lewis JC, Szejda P, ve diğerleri. (1981). "Activation of lysosomal acid phosphatase of eosinophil leukocytes". Lab. Invest. 44 (5). ss. 403-9. PMID 6164873.
Chappard D, Alexandre C, Riffat G (1983). "Histochemical identification of osteoclasts. Review of current methods and reappraisal of a simple procedure for routine diagnosis on undecalcified human iliac bone biopsies". Basic and Applied Histochemistry. 27 (2). ss. 75-85. PMID 6193776.
Moszczyński P, Lisiewicz J (1984). "Beta-glucuronidase of lymphocytes in ontogenetic development of man". Arch. Immunol. Ther. Exp. (Warsz.). 31 (2). ss. 171-6. PMID 6651479.
Radzun HJ, Parwaresch MR (1981). "Isoelectric focusing pattern of acid phosphatase and acid esterase in human blood cells, including thymocytes, T lymphocytes, and B lymphocytes". Exp. Hematol. 8 (6). ss. 737-41. PMID 6970673.
Andersson B, Wentland MA, Ricafrente JY, ve diğerleri. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1). ss. 107-13. doi:10.1006/abio.1996.0138. PMID 8619474.
Whitelock RB, Fukuchi T, Zhou L, ve diğerleri. (1997). "Cathepsin G, acid phosphatase, and alpha 1-proteinase inhibitor messenger RNA levels in keratoconus corneas". Invest. Ophthalmol. Vis. Sci. 38 (2). ss. 529-34. PMID 9040486.
Yu W, Andersson B, Worley KC, ve diğerleri. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4). ss. 353-8. doi:10.1101/gr.7.4.353. PMC 139146 . PMID 9110174.
Obermüller S, Kiecke C, von Figura K, Höning S (2002). "The tyrosine motifs of Lamp 1 and LAP determine their direct and indirect targeting to lysosomes". J. Cell Sci. 115 (Pt 1). ss. 185-94. doi:10.1242/jcs.115.1.185. PMID 11801736.
Strausberg RL, Feingold EA, Grouse LH, ve diğerleri. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26). ss. 16899-903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241 . PMID 12477932.
Gerhard DS, Wagner L, Feingold EA, ve diğerleri. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B). ss. 2121-7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000134575 - Ensembl, May 2017

[2] "İnsan PubMed Başvurusu:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Fare PubMed Başvurusu:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid975882-4] Shows TB, Brown JA, Lalley PA (Dec 1976). "Assignment and linear order of human acid phosphatase-2, esterase A4, and lactate dehydrogenase A genes on chromosome 11". Cytogenet Cell Genet. 16 (1–5). ss. 231-4. doi:10.1159/000130598. PMID 975882.

[entrez-5] "Entrez Gene: ACP2 acid phosphatase 2, lysosomal". 2 Kasım 2008 tarihinde kaynağından arşivlendi.