POLE2

POLE2
Identifiers
Aliases	POLE2, DPE2, polymerase (DNA) epsilon 2, accessory subunit, DNA polymerase epsilon 2, accessory subunit
External IDs	OMIM: 602670; MGI: 1197514; GeneCards: POLE2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2V6Z
Gene location (Human)
Chr.	Chromosome 14 (human)
End	49,688,422 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	69,274,969 bp
RNA expression pattern
	Top expressed in
	gonad; ; testicle; ; ventricular zone; ; secondary oocyte; ; mucosa of transverse colon; ; rectum; ; ganglionic eminence; ; right uterine tube; ; mucosa of esophagus; ; ectocervix;
	Top expressed in
	tongue muscle; ; choroidal fissure; ; zygote; ; tail of embryo; ; spermatid; ; genital tubercle; ; blastocyst; ; embryo; ; morula; ; ventricular zone;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; DNA binding; nucleotidyltransferase activity; protein binding; DNA-directed DNA polymerase activity;
Cellular component	intracellular membrane-bounded organelle; nucleus; nucleoplasm; nuclear body; epsilon DNA polymerase complex;
Biological process	DNA repair; error-prone translesion synthesis; DNA replication; DNA-dependent DNA replication; G1/S transition of mitotic cell cycle; DNA replication initiation; telomere maintenance via semi-conservative replication;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	5427
	18974
	ENSG00000100479
	ENSMUSG00000020974
	P56282
	O54956
	NM_001197330; NM_001197331; NM_002692; NM_001348384; NM_001348385
	NM_011133
	NP_001184259; NP_001184260; NP_002683; NP_001335313; NP_001335314
	NP_035263
	Wikidata
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