Enoticumab
Bibliografia
(EN ) Huang J, Hu W, Hu L, Previs RA, Dalton HJ, Yang XY, Sun Y, McGuire M, Rupaimoole R, Nagaraja AS, Kang Y, Liu T, Nick AM, Jennings NB, Coleman RL, Jaffe RB, Sood AK, DLL4 Inhibition plus Aflibercept Markedly Reduces Ovarian Tumor Growth , in Mol. Cancer Ther. , vol. 15, n. 6, giugno 2016, pp. 1344-1352, DOI :10.1158/1535-7163.MCT-15-0144 , PMID 27009216 .
(EN ) Kuhnert F, Chen G, Coetzee S, Thambi N, Hickey C, Shan J, Kovalenko P, Noguera-Troise I, Smith E, Fairhurst J, Andreev J, Kirshner JR, Papadopoulos N, Thurston G, DLL4 Blockade in Stromal Cells Mediates Antitumor Effects in Preclinical Models of Ovarian Cancer , in Cancer Research , vol. 75, n. 19, ottobre 2015, pp. 4086-4096, DOI :10.1158/0008-5472.CAN-14-3773 , PMID 26377940 .
(EN ) Chiorean EG, LoRusso P, Strother RM, Diamond JR, Younger A, Messersmith WA, Adriaens L, Liu L, Kao RJ, DiCioccio AT, Kostic A, Leek R, Harris A, Jimeno A, A Phase I First-in-Human Study of Enoticumab (REGN421), a Fully Human Delta-like Ligand 4 (DLL4) Monoclonal Antibody in Patients with Advanced Solid Tumors , in Clin. Cancer Res. , vol. 21, n. 12, giugno 2015, pp. 2695-2703, DOI :10.1158/1078-0432.CCR-14-2797 , PMID 25724527 .
(EN ) Miles KM, Seshadri M, Ciamporcero E, Adelaiye R, Gillard B, Sotomayor P, Attwood K, Shen L, Conroy D, Kuhnert F, Lalani AS, Thurston G, Pili R, DLL4 blockade potentiates the anti-tumor effects of VEGF inhibition in renal cell carcinoma patient-derived xenografts , vol. 9, n. 11, 2014, p. e112371, DOI :10.1371/journal.pone.0112371 , PMID 25393540 .