Metfendrazine

Metfendrazine
Clinical data
Other namesMethphendrazine; HM-11; MO-482; N-Aminomethamphetamine; Methamphetamine hydrazide; N-Amino-N-methylamphetamine
Routes of
administration		Oral
ATC code
  • none
Legal status
Legal status
  • In general: uncontrolled
Identifiers
  • 1-methyl-1-(1-methyl-2-phenyl-ethyl)hydrazine
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC10H16N2
Molar mass164.252 g·mol−1

Metfendrazine (developmental code names HM-11, MO-482), also known as methphendrazine, is an irreversible and nonselective monoamine oxidase inhibitor (MAOI) of the hydrazine family. It was investigated as an antidepressant, but was never marketed.

Chemistry

Metfendrazine, also known as methamphetamine hydrazide, is a phenethylamine, amphetamine, and hydrazine derivative.

It is an analogue and derivative of phenelzine (phenethylamine hydrazide) and pheniprazine (amphetamine hydrazide), as well as of phenethylamine, amphetamine, and methamphetamine.

References

  1. ↑ Miquel J, Mijan CD (1962). "Metfendrazine, a new inhibitor of monoamine oxidase". Archivos del Instituto de Farmacología Experimental. 14. Madrid: 47–59.
  2. ↑ Kothari NJ, Saunders JC, Kline NS, Griffen JA (October 1960). "A comparison of perphenazine, proketazine, nialamide and MO-482 in chronic schizophrenics". The American Journal of Psychiatry. 117 (4): 358–360. doi:10.1176/ajp.117.4.358. PMID 13753478.