TMX3

TMX3
Identifiers
Aliases	TMX3, PDIA13, TXNDC10, thioredoxin related transmembrane protein 3
External IDs	OMIM: 616102; MGI: 2442418; GeneCards: TMX3
Enzyme activity
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	90,561,391 bp
RNA expression pattern
	n/a
	Top expressed in
	otolith organ; ; utricle; ; hand; ; superior cervical ganglion; ; olfactory epithelium; ; endothelial cell of lymphatic vessel; ; supraoptic nucleus; ; Epithelium of choroid plexus; ; substantia nigra; ; dorsomedial hypothalamic nucleus;
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; isomerase activity; thiol oxidase activity; protein disulfide isomerase activity;
Cellular component	integral component of membrane; cell surface; endoplasmic reticulum membrane; endoplasmic reticulum; membrane; platelet alpha granule membrane; plasma membrane;
Biological process	peptidyl-cysteine oxidation; protein folding; response to endoplasmic reticulum stress; cell redox homeostasis; platelet degranulation;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	54495
	67988
	ENSG00000166479
	ENSMUSG00000024614
	Q96JJ7
	Q8BXZ1
	NM_019022
	NM_198295
NP_061895; NP_001337441; NP_001337442; NP_001337443; NP_001337444;
	NP_001337445; NP_001337446
	NP_938037
	Wikidata
View/Edit Human	View/Edit Mouse

Protein disulfide-isomerase TMX3 is an enzyme that in humans is encoded by the TMX3 gene.

References

1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000024614 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Haugstetter J, Blicher T, Ellgaard L (March 2005). "Identification and characterization of a novel thioredoxin-related transmembrane protein of the endoplasmic reticulum". The Journal of Biological Chemistry. 280 (9): 8371–8380. doi:10.1074/jbc.M413924200. PMID 15623505.
↑ "Entrez Gene: TXNDC10 thioredoxin domain containing 10".

Hartley JL, Temple GF, Brasch MA (November 2000). "DNA cloning using in vitro site-specific recombination". Genome Research. 10 (11): 1788–1795. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, et al. (March 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Research. 11 (3): 422–435. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Nagase T, Nakayama M, Nakajima D, Kikuno R, Ohara O (April 2001). "Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 8 (2): 85–95. doi:10.1093/dnares/8.2.85. PMID 11347906.
Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, et al. (October 2004). "From ORFeome to biology: a functional genomics pipeline". Genome Research. 14 (10B): 2136–2144. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, et al. (January 2006). "The LIFEdb database in 2006". Nucleic Acids Research. 34 (Database issue): D415–D418. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
Haugstetter J, Maurer MA, Blicher T, Pagac M, Wider G, Ellgaard L (November 2007). "Structure-function analysis of the endoplasmic reticulum oxidoreductase TMX3 reveals interdomain stabilization of the N-terminal redox-active domain". The Journal of Biological Chemistry. 282 (46): 33859–33867. doi:10.1074/jbc.M706442200. PMID 17881353.

This article on a gene on human chromosome 18 is a stub. You can help Wikipedia by adding missing information.

[refGRCm38Ensembl-1] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000024614 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid15623505-4] Haugstetter J, Blicher T, Ellgaard L (March 2005). "Identification and characterization of a novel thioredoxin-related transmembrane protein of the endoplasmic reticulum". The Journal of Biological Chemistry. 280 (9): 8371–8380. doi:10.1074/jbc.M413924200. PMID 15623505.

[entrez-5] "Entrez Gene: TXNDC10 thioredoxin domain containing 10".

TMX3

References

Further reading