TMX4

TMX4
Identifiers
Aliases	TMX4, DJ971N18.2, PDIA14, TXNDC13, thioredoxin related transmembrane protein 4
External IDs	OMIM: 616766; MGI: 106558; GeneCards: TMX4
Gene location (Human)
Chr.	Chromosome 20 (human)
End	8,019,805 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	134,486,065 bp
RNA expression pattern
	Top expressed in
	germinal epithelium; ; Brodmann area 23; ; seminal vesicula; ; tail of epididymis; ; Epithelium of choroid plexus; ; caput epididymis; ; endothelial cell; ; cardiac muscle tissue of right atrium; ; parotid gland; ; middle temporal gyrus;
	Top expressed in
	dorsomedial hypothalamic nucleus; ; paraventricular nucleus of hypothalamus; ; arcuate nucleus; ; ventromedial nucleus; ; lateral hypothalamus; ; median eminence; ; suprachiasmatic nucleus; ; ventral tegmental area; ; mammillary body; ; anterior amygdaloid area;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein disulfide isomerase activity;
Cellular component	membrane; integral component of membrane; endoplasmic reticulum;
Biological process	protein folding; response to endoplasmic reticulum stress; cell redox homeostasis;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	56255
	52837
	ENSG00000125827
	ENSMUSG00000034723
	Q9H1E5
	Q8C0L0
	NM_021156
	NM_029148
	NP_066979
	NP_083424
	Wikidata
View/Edit Human	View/Edit Mouse

Thioredoxin-related transmembrane protein 4 also known as thioredoxin domain-containing protein 13 is a protein that in humans is encoded by the TMX4 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000125827 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000034723 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: TXNDC13 thioredoxin domain containing 13".

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Hirosawa M, Nagase T, Ishikawa K, et al. (2000). "Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain". DNA Res. 6 (5): 329–36. doi:10.1093/dnares/6.5.329. PMID 10574461.
Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. Bibcode:2001Natur.414..865D. doi:10.1038/414865a. PMID 11780052.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.

This article on a gene on human chromosome 20 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000125827 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000034723 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: TXNDC13 thioredoxin domain containing 13".

TMX4

References

Further reading