GAMMA (drug)

GAMMA
Clinical data
Other namesγ; homo-MDPEA; 3,4-Methylenedioxyphenyl-propylamine; 1-Amino-3-(3,4-methylenedioxyphenyl)propane
Routes of
administration		Oral
Drug classPsychoactive drug
ATC code
  • None
Pharmacokinetic data
Duration of action4 hours
Identifiers
  • 3-(1,3-benzodioxol-5-yl)propan-1-amine
CAS Number
PubChem CID
ChemSpider
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC10H13NO2
Molar mass179.219 g·mol−1
3D model (JSmol)
  • C1OC2=C(O1)C=C(C=C2)CCCN
  • InChI=1S/C10H13NO2/c11-5-1-2-8-3-4-9-10(6-8)13-7-12-9/h3-4,6H,1-2,5,7,11H2
  • Key:CLJLCLGOWKOKJF-UHFFFAOYSA-N

GAMMA, also known as homo-MDPEA or as 3,4-methylenedioxyphenylpropylamine, is a psychoactive drug belonging to the 3-phenylpropylamine family (compounds related to phenethylamines with a three-carbon chain) and a compound related to methylenedioxyphenethylamines.

Use and effects

In his book PiHKAL (Phenethylamines I Have Known and Loved), Alexander Shulgin lists GAMMA's dose as 200 mg orally and its duration as 4 hours. The effects of GAMMA have been reported to include "some physical ill-at-ease, possible time distortion, and a feeling of being keenly aware of one's surroundings".

Chemistry

Analogues

Analogues of GAMMA include homo-MDA and homo-MDMA, among others.

History

GAMMA was first described in the scientific literature by Alexander Shulgin and Peyton Jacob III by 1982. Subsequently it was described further by Shulgin in his book PiHKAL (Phenethylamines I Have Known and Loved) in 1991.

See also

References

  1. 1 2 3 4 5 6 7 Shulgin AT, Shulgin A. "entry 100: GAMMA". PiHKAL: A Chemical Love Story. Book II. Isomer Design [Internet]. Retrieved 2026-09-09.
  2. ↑ Shulgin A. The Shulgin Index (The 23 homo-phenylethylamines compounds in table 10, page 358).
  3. 1 2 Shulgin AT, Jacob P (March 1982). "1-(3,4-methylenedioxyphenyl)-3-aminobutane: a potential toxicological problem". J Toxicol Clin Toxicol. 19 (1): 109–110. doi:10.3109/15563658208990371. PMID 7154137.