SYT4

SYT4
Identifiers
Aliases	SYT4, HsT1192, synaptotagmin 4
External IDs	OMIM: 600103; MGI: 101759; GeneCards: SYT4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1UGK
Gene location (Human)
Chr.	Chromosome 18 (human)
End	43,277,535 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	31,580,459 bp
RNA expression pattern
	Top expressed in
	cerebellar vermis; ; endothelial cell; ; cerebellar hemisphere; ; Brodmann area 23; ; right hemisphere of cerebellum; ; Brodmann area 46; ; middle temporal gyrus; ; superior frontal gyrus; ; superior vestibular nucleus; ; islet of Langerhans;
	Top expressed in
	lobe of cerebellum; ; cerebellar vermis; ; ventral tegmental area; ; pineal gland; ; dorsomedial hypothalamic nucleus; ; habenula; ; anterior amygdaloid area; ; ventromedial nucleus; ; paraventricular nucleus of hypothalamus; ; lateral hypothalamus;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	calcium ion binding; clathrin binding; phosphatidylserine binding; metal ion binding; protein binding; SNARE binding; syntaxin-1 binding; syntaxin binding; syntaxin-3 binding; protein homodimerization activity; protein heterodimerization activity; calcium-dependent phospholipid binding;
Cellular component	integral component of membrane; intracellular membrane-bounded organelle; membrane; synapse; synaptic vesicle membrane; cell junction; perinuclear region of cytoplasm; neuron projection; dense core granule; cytoplasmic vesicle; dendrite; Golgi apparatus; vesicle; axon; plasma membrane; synaptic vesicle; integral component of Golgi membrane; integral component of synaptic vesicle membrane; secretory granule membrane; dense core granule membrane; somatodendritic compartment; soma; neuron projection terminus; exocytic vesicle; astrocyte projection; microvesicle; glutamatergic synapse; integral component of neuronal dense core vesicle membrane;
Biological process	cell differentiation; brain development; positive regulation of dendrite extension; negative regulation of vesicle fusion; neurotransmitter secretion; exocytosis; vesicle fusion; calcium ion-regulated exocytosis of neurotransmitter; memory; positive regulation of glutamate secretion; regulation of dopamine secretion; regulation of endocytosis; regulation of vesicle fusion; negative regulation of catecholamine secretion; positive regulation of calcium ion-dependent exocytosis; negative regulation of neurotransmitter secretion; negative regulation of short-term neuronal synaptic plasticity; vesicle fusion with vesicle; secretory granule maturation; negative regulation of protein secretion; negative regulation of retrograde trans-synaptic signaling by neuropeptide; regulation of calcium ion-dependent exocytosis; negative regulation of calcium ion-dependent exocytosis; trans-synaptic signaling by BDNF, modulating synaptic transmission; vesicle-mediated transport; calcium-ion regulated exocytosis; cellular response to calcium ion; regulation of presynaptic dense core granule exocytosis; negative regulation of dense core granule exocytosis; positive regulation of dense core granule exocytosis; negative regulation of synaptic vesicle exocytosis;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	6860
	20983
	ENSG00000132872
	ENSMUSG00000024261
	Q9H2B2
	P40749
	NM_020783
	NM_009308
	NP_065834
	NP_033334
	Wikidata
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