DTX2

DTX2
Identifiers
Aliases	DTX2, RNF58, deltex 2, E3 ubiquitin ligase, deltex E3 ubiquitin ligase 2
External IDs	OMIM: 613141; MGI: 1921448; GeneCards: DTX2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1V87
Enzyme activity
Gene location (Human)
Chr.	Chromosome 7 (human)
End	76,505,995 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	136,061,726 bp
RNA expression pattern
	Top expressed in
	mucosa of transverse colon; ; olfactory zone of nasal mucosa; ; sural nerve; ; right testis; ; minor salivary glands; ; left testis; ; blood; ; skin of leg; ; skin of abdomen; ; vagina;
	Top expressed in
	secondary oocyte; ; primary oocyte; ; zygote; ; Rostral migratory stream; ; condyle; ; internal carotid artery; ; fossa; ; external carotid artery; ; hair follicle; ; motor neuron;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	zinc ion binding; protein binding; metal ion binding; transferase activity;
Cellular component	cytoplasm; nuclear membrane; nucleus; nucleoplasm;
Biological process	Notch signaling pathway; protein ubiquitination;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	113878
	74198
	ENSG00000282379; ENSG00000091073
	ENSMUSG00000004947
	Q86UW9
	Q8R3P2
	NM_001102594; NM_001102595; NM_001102596; NM_020892
	NM_001256096; NM_001256097; NM_001256098; NM_023742
	NP_001096064; NP_001096065; NP_001096066; NP_065943
	NP_001243025; NP_001243026; NP_001243027; NP_076231
	Wikidata
View/Edit Human	View/Edit Mouse

Protein deltex-2 also known as E3 ubiquitin-protein ligase DTX2 is an enzyme that in humans is encoded by the DTX2 gene.

DTX2 functions as a ubiquitin E3 ligase in conjunction with the E2 enzyme UBCH5A.

References

DTX2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article on a gene on human chromosome 7 is a stub. You can help Wikipedia by adding missing information.