IL17RA Protein-coding gene in the species Homo sapiens
IL17RA Identifiers Aliases IL17RA External IDs OMIM : 605461 ; MGI : 107399 ; GeneCards : IL17RA Gene location (Mouse ) Chr. Chromosome 6 (mouse) Band 6 F1| 6 56.95 cM Start 120,440,208 bp End 120,464,520 bp
Wikidata
Interleukin 17 receptor A , also known as IL17RA and CDw217 (cluster of differentiation w217), is a human gene .
Interleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure.
Further reading
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