SLC8A1

SLC8A1
Identifiants
Alias	SLC8A1
IDs externes	OMIM: 182305 MGI: 107956 HomoloGene: 69090 GeneCards: SLC8A1
Position du gène (humain)
Chr.	Chromosome 2 humain
Fin	40,611,053 bp
Position du gène (souris)
Chr.	Chromosome 17 (souris)
Fin	82,045,806 bp
Expression génique
	Fortement exprimé dans
	ventricule droit; ; cellule endothéliale; ; Veine saphène; ; Brodmann area 23; ; epithelium of colon; ; veine cave; ; myocarde; ; gyrus postcentral; ; cardiac muscle tissue of right atrium; ; gyrus temporal moyen;
	Fortement exprimé dans
	lateral septal nucleus; ; cardiac muscle tissue of left ventricle; ; lumbar subsegment of spinal cord; ; ventromedial nucleus; ; corps géniculé latéral; ; lateral hypothalamus; ; substantia nigra; ; pontine nuclei; ; medullary collecting duct; ; corps mamillaires;
	Plus de données d'expression de référence
	n/a
Gene Ontology
Fonction moléculaire	ankyrin binding; calcium liaison ionique; liaison ion métal; antiporter activity; fixation de la calmoduline; transmembrane transporter binding; cytoskeletal protein binding; liaison protéique; calcium:sodium antiporter activity; ion antiporter activity involved in regulation of postsynaptic membrane potential; calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration;
Composant cellulaire	sarcolemma; integral component of membrane; mitochondrie; prolongement cellulaire; dendritic shaft; integral component of plasma membrane; épine dendritique; membrane; microtubule; Z discdkac; intercalated disc; T-tubule; nucléoplasme; membrane plasmique; membrane postsynaptique; integral component of postsynaptic membrane;
Processus biologique	response to muscle stretch; contraction musculaire; response to hypoxia; cellular response to caffeine; telencephalon development; positive regulation of fibroblast migration; cellular response to cAMP; regulation of cardiac conduction; response to ATP; regulation of sodium ion transport; regulation of heart rate; vascular associated smooth muscle contraction; response to immobilization stress; cellular sodium ion homeostasis; positive regulation of the force of heart contraction; positive regulation of bone mineralization; positive regulation of cytosolic calcium ion concentration; relaxation of smooth muscle; cellular calcium ion homeostasis; calcium ion homeostasis; calcium ion transport into cytosol; communication cellulaire; cell communication by electrical coupling involved in cardiac conduction; ion transport; regulation of calcium ion transport; regulation of cell communication by electrical coupling; regulation of cardiac muscle contraction by calcium ion signaling; cardiac muscle cell development; membrane depolarization during cardiac muscle cell action potential; cellular response to hypoxia; response to glucose; response to nutrient; response to hydrogen peroxide; calcium ion import; sodium ion transport; calcium ion transport; negative regulation of cytosolic calcium ion concentration; cardiac muscle contraction; sodium ion transmembrane transport; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; regulation of the force of heart contraction; calcium ion transmembrane transport; relaxation of cardiac muscle; transport transmembranaire; cellular response to reactive oxygen species; calcium ion export; Potentiel postsynaptique; sodium ion export across plasma membrane; sodium ion import across plasma membrane; regulation of postsynaptic cytosolic calcium ion concentration;
	Sources:Amigo / QuickGO
Orthologues
	6546
	20541
	ENSG00000183023
	ENSMUSG00000054640
	P32418
	P70414
NM_001112800; NM_001112801; NM_001112802; NM_001252624; NM_021097;
	NM_001351483; NM_001351484; NM_001351485; NM_001351486; NM_001351487; NM_001351488; NM_001351489; NM_001351490; NM_001351491; NM_001351492; NM_001351493; NM_001351494; NM_001372263; NM_001394103; NM_001394104; NM_001394105; NM_001394106; NM_001394107
	NM_001112798; NM_001286684; NM_011406
NP_001106271; NP_001106272; NP_001106273; NP_001239553; NP_066920;
	NP_001338412; NP_001338413; NP_001338414; NP_001338415; NP_001338416; NP_001338417; NP_001338418; NP_001338419; NP_001338420; NP_001338421; NP_001338422; NP_001338423; NP_001359192
	NP_001106269; NP_001273613; NP_035536
	Wikidata
Voir/Editer Humain	Voir/Editer Souris