MFN2

MFN2
Identifiants
Alias	MFN2
IDs externes	OMIM: 608507 MGI: 2442230 HomoloGene: 8915 GeneCards: MFN2
Position du gène (humain)
Chr.	Chromosome 1 humain
Fin	12,015,211 bp
Position du gène (souris)
Chr.	Chromosome 4 (souris)
Fin	147,989,161 bp
Expression génique
	Fortement exprimé dans
	apex of heart; ; ventricule gauche; ; muscle de la cuisse; ; auricule de l'oreillette droite; ; muscle gastrocnémien; ; myocardium of left ventricle; ; cardiac muscle tissue of right atrium; ; nerf optique; ; Skeletal muscle tissue of rectus abdominis; ; diaphragme;
	Fortement exprimé dans
	septum interventriculaire; ; myocardium of ventricle; ; muscle digastrique; ; muscle de la cuisse; ; skeletal muscle tissue; ; muscle temporal; ; muscle quadriceps fémoral; ; muscle soléaire; ; muscle vaste latéral; ; ventricule droit;
	Plus de données d'expression de référence
	; ;
	Plus de données d'expression de référence
Gene Ontology
Fonction moléculaire	liaison nucléotide; GTP binding; liaison protéique; activité hydrolase; ubiquitin protein ligase binding; GTPase activity;
Composant cellulaire	cytosol; membrane; microtubule cytoskeleton; membrane mitochondrial externe; mitochondrie; integral component of membrane; intrinsic component of mitochondrial outer membrane;
Processus biologique	mitochondrial fusion; negative regulation of smooth muscle cell proliferation; protein localization to phagophore assembly site; mitochondrion localization; protein targeting to mitochondrion; coagulation sanguine; blastocyst formation; negative regulation of Ras protein signal transduction; autophagie; response to unfolded protein; macroautophagy; mitochondrial membrane organization; camera-type eye morphogenesis; apoptose; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization; positive regulation of vascular associated smooth muscle cell proliferation; positive regulation of vascular associated smooth muscle cell apoptotic process; positive regulation of cold-induced thermogenesis;
	Sources:Amigo / QuickGO
Orthologues
	9927
	170731
	ENSG00000116688
	ENSMUSG00000029020
	O95140
	Q80U63
	NM_001127660; NM_014874
NM_001285920; NM_001285921; NM_001285922; NM_001285923; NM_133201;
	NM_001355590; NM_001355591
	NP_001121132; NP_055689
NP_001272849; NP_001272850; NP_001272851; NP_001272852; NP_573464;
	NP_001342519; NP_001342520
	Wikidata
Voir/Editer Humain	Voir/Editer Souris